Quantitative in vivo mapping of myocardial mitochondrial membrane potential
نویسندگان
چکیده
منابع مشابه
Correction: Quantitative in vivo mapping of myocardial mitochondrial membrane potential
[This corrects the article DOI: 10.1371/journal.pone.0190968.].
متن کاملQuantitative in vivo mapping of myocardial mitochondrial membrane potential
BACKGROUND Mitochondrial membrane potential (ΔΨm) arises from normal function of the electron transport chain. Maintenance of ΔΨm within a narrow range is essential for mitochondrial function. Methods for in vivo measurement of ΔΨm do not exist. We use 18F-labeled tetraphenylphosphonium (18F-TPP+) to measure and map the total membrane potential, ΔΨT, as the sum of ΔΨm and cellular (ΔΨc) electri...
متن کاملMyocardial imaging for mitochondrial membrane potential.
c p p r p q m Rest and stress myocardial perfusion imaging, described nearly 4 decades ago (1), is now performed in 9 million people annually in the United States (2). The procedure provides clinically useful data regardless of whether the tracer is a monovalent cation such as potassium, thallium, or rubidium; a highly diffusible agent such as O-labeled water; an amino acid precursor such as am...
متن کاملThe effect of aminoguanidine on sperm motility and mitochondrial membrane potential in varicocelized rats
Objective(s): Increased levels of nitric oxide (NO) in the testicular veins of people suffering from varicocele have already been reported. However, the role of NO-synthase (NOS) isozymes and their inhibitors have not been extensively studied. We aimed to evaluate the inhibitory effects of aminoguanidine (AG), on sperm motility, vitality, and mitochondrial membrane potential (MMP) in varicoceli...
متن کاملTransient Receptor Potential Vanilloid 1 Regulates Mitochondrial Membrane Potential and Myocardial Reperfusion Injury
BACKGROUND The transient receptor potential vanilloid 1 (TRPV1) mediates cellular responses to pain, heat, or noxious stimuli by calcium influx; however, the cellular localization and function of TRPV1 in the cardiomyocyte is largely unknown. We studied whether myocardial injury is regulated by TRPV1 and whether we could mitigate reperfusion injury by limiting the calcineurin interaction with T...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0190968